A series of investigations aimed at identifying the best way to measure TBE risk among humans.
Tick-borne encephalitis risk based on different data sources
I started this project during my Master of Science thesis in 2004, when I developed a model to predict tick-borne encephalitis (TBE) risk in Poland based on landscape, meteorologic and socio-demographic characteristics. In 2005-2017, I developed a series of investigations aimed at identifying the best way to measure TBE risk and especially how to improve surveillance. Within this project I evaluated the existing surveillance system, I implemented serological surveys of humans and household animals, collected representative pools of ticks to measure TBE virus prevalence in ticks, I evaluated clinical management of patients and vaccination programmes. Within this project I also carried out a unique nationwide case-control study of TBE risk factors. As a project closure, I fitted a powerful statistical model trying to predict TBE risk based on a set of landscape, meteorological and socio-demographic characterists measured at the lowest possible resolution. It was probably my most impactful contribution, which resulted in two theses, a dozen of peer-reviewed publications and some 30 presentations on peer-reviewed conferences.
Why does it matter?
These investigations can help in better monitoring of tick-borne encephalitis risk areas. When efficiently monitored, municipalities could offer vaccination to people at risk and GPs could offer vaccination to tourists visiting those areas.
Related to
Surveillance of human TBE cases:
Stefanoff et al. Przegl Epidemiol 2005; 60 Suppl. 1: 151-159.
Stefanoff et al. Parasit Vectors 2013; 6: 180: doi: 10.1186/1756-3305-6-180.
Stefanoff et al. Cent Eur J Public Health 2014; 22(1): 54-9.
Assessing human risk based on serological surveys, surveys of ticks and household animals:
Stefanoff et al. Int J Med Microbiol 2008; 298 (Suppl. 1): 102-107.
Stefanoff et al. Zoonoses Public Health 2013; 60(3): 215-26.
Other investigations (risk factors, clinical management or vaccination programmes):
Overall conclusions and modelling of TBE risk:
Master of Science in Epidemiology, SUNY at Albany School of Public Health, Albany, NY, 2004.
Stefanoff et al. Przegl Epidemiol 2008; 62 Supl. 1: 112-121.
Habilitation degree in health sciences, Warsaw Medical University, Warsaw, 2018.
Stefanoff et al. Int J Environ Res Public Health 2018; 15(4). pii: E677.